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Recent Webinars

Finding the needle in the haystack: The use of multi-gene panels in oncology

Heather Hampel, MS, CGC and Tuya Pal, MD
May 12, 2014
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The use of multi-gene panels in hereditary cancer clinics is increasing. Heather Hampel, MS, CGC and Tuya Pal, MD will present cases from their clinical experience that have utilized panel testing. The speakers will highlight the potential benefits of panels as well as difficulties including managing patient expectations, dealing with positive results in moderate penetrance genes and multiple VUSes per patient.

Can multi-gene panels allow us to provide additional genetic guidance and screening to improve patient care?

Allison Kurian, MD, MSc
May 08, 2014
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New research findings from Stanford published in JCO on multi-gene panels for hereditary cancers: what have we learned about improving patient care?

According to a new publication from Stanford in the Journal of Clinical Oncology, as many as 10 percent of women with a personal or family history of breast or ovarian cancer have at least one genetic mutation that, if known, would prompt their doctors to recommend changes in their care, according to a new study by researchers at the Stanford University School of Medicine.

The women in the study did not have mutations in BRCA1 or BRCA2 (mutations in these genes are strongly associated with hereditary breast and ovarian cancer), but they did have mutations in other cancer-associated genes.

The study was conducted using what’s known as a multiple-gene panel to quickly and cheaply sequence just a few possible genetic culprits selected by researchers based on what is known about a disease. Although such panels are becoming widely clinically available, it’s not been clear whether their use can help patients or affect medical recommendations.

This seminar aims to answer those questions, both from the research study, featuring lead author Dr. Allison Kurian.