Proactive

Proactive genetic testing offers healthy adults without a strong personal or family history of disease an opportunity to learn about how their genes could potentially impact their health.

Invitae offers testing options that analyze genes that are well-established indicators of a significantly increased risk of developing hereditary cancers, cardiovascular conditions, and other medically important disorders. Learn more

147 genes

Invitae Genetic Health Screen

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Our most comprehensive proactive panel for healthy individuals analyzing over 145 genes related to inherited cancer and cardiovascular conditions, as well as several other medically actionable conditions.

GENES TESTED:

ACTA2 ACTC1 ACTN2 ACVRL1 APC APOB ATM ATP7B AXIN2 BAG3 BAP1 BARD1 BMPR1A BMPR2 BRCA1 BRCA2 BRIP1 CACNA1C CACNA1S CACNB2 CALM1 CALM2 CALM3 CASQ2 CAV1 CAV3 CDC73 CDH1 CDK4 CDKN2A CHEK2 COL3A1 CRYAB CSRP3 DES DICER1 DMD DSC2 DSG2 DSP EMD ENG EPCAM F2 F5 F9 FBN1 FH FHL1 FLCN FLNC GDF2 GLA GPD1L GREM1 HAMP HCN4 HFE HJV HOXB13 JUP KCNE1 KCNE2 KCNH2 KCNJ2 KCNQ1 KIT LAMP2 LDLR LDLRAP1 LMNA MAX MEN1 MET MITF MLH1 MSH2 MSH3 MSH6 MUTYH MYBPC3 MYH11 MYH7 MYL2 MYL3 MYLK NBN NF1 NF2 NKX2-5 NTHL1 OTC PALB2 PCSK9 PDGFRA PKP2 PLN PMS2 POLD1 POLE PRKAG2 PRKAR1A PRKG1 PROC PROS1 PTCH1 PTEN RAD51C RAD51D RB1 RBM20 RET RYR1 RYR2 SCN5A SDHA SDHAF2 SDHB SDHC SDHD SERPINA1 SERPINC1 SGCD SLC40A1 SMAD3 SMAD4 SMARCA4 SMARCB1 STK11 TCAP TFR2 TGFB2 TGFB3 TGFBR1 TGFBR2 TMEM127 TMEM43 TNNC1 TNNI3 TNNT2 TP53 TPM1 TSC1 TSC2 VCL VHL WT1

61 genes

Invitae Cancer Screen

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Proactive panel for healthy individuals analyzing over 60 cancer-related genes.

GENES TESTED:

APC ATM AXIN2 BAP1 BARD1 BMPR1A BRCA1 BRCA2 BRIP1 CDC73 CDH1 CDK4 CDKN2A CHEK2 DICER1 EPCAM FH FLCN GREM1 HOXB13 KIT MAX MEN1 MET MITF MLH1 MSH2 MSH3 MSH6 MUTYH NBN NF1 NF2 NTHL1 PALB2 PDGFRA PMS2 POLD1 POLE PRKAR1A PTCH1 PTEN RAD51C RAD51D RB1 RET SDHA SDHAF2 SDHB SDHC SDHD SMAD4 SMARCA4 SMARCB1 STK11 TMEM127 TP53 TSC1 TSC2 VHL WT1

77 genes

Invitae Cardio Screen

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Proactive panel for healthy individuals analyzing over 75 genes related to hereditary forms of cardiovascular disease.

GENES TESTED:

ACTA2 ACTC1 ACTN2 ACVRL1 APOB BAG3 BMPR2 CACNA1C CACNB2 CALM1 CALM2 CALM3 CASQ2 CAV1 CAV3 COL3A1 CRYAB CSRP3 DES DMD DSC2 DSG2 DSP EMD ENG F2 F5 F9 FBN1 FHL1 FLNC GDF2 GLA GPD1L HCN4 JUP KCNE1 KCNE2 KCNH2 KCNJ2 KCNQ1 LAMP2 LDLR LDLRAP1 LMNA MYBPC3 MYH11 MYH7 MYL2 MYL3 MYLK NKX2-5 PCSK9 PKP2 PLN PRKAG2 PRKG1 PROC PROS1 RBM20 RYR2 SCN5A SERPINC1 SGCD SMAD3 SMAD4 TCAP TGFB2 TGFB3 TGFBR1 TGFBR2 TMEM43 TNNC1 TNNI3 TNNT2 TPM1 VCL

11 genes

Invitae First Tier Population Screen

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Proactive panel for healthy individuals analyzing 11 genes related to inherited cancers and familial hypercholesterolemia.

GENES TESTED:

APOB BRCA1 BRCA2 EPCAM LDLR LDLRAP1 MLH1 MSH2 MSH6 PCSK9 PMS2

59 genes

Invitae ACMG Actionable Disorders Panel

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A panel of 59 medically actionable genes prescribed by the American College of Medical Genetics and Genomics.

GENES TESTED:

ACTA2 ACTC1 APC APOB ATP7B BMPR1A BRCA1 BRCA2 CACNA1S COL3A1 DSC2 DSG2 DSP FBN1 GLA KCNH2 KCNQ1 LDLR LMNA MEN1 MLH1 MSH2 MSH6 MUTYH MYBPC3 MYH11 MYH7 MYL2 MYL3 NF2 OTC PCSK9 PKP2 PMS2 PRKAG2 PTEN RB1 RET RYR1 RYR2 SCN5A SDHAF2 SDHB SDHC SDHD SMAD3 SMAD4 STK11 TGFBR1 TGFBR2 TMEM43 TNNI3 TNNT2 TP53 TPM1 TSC1 TSC2 VHL WT1