Invitae Preimplantation Genetic Testing

A critical step in optimizing IVF outcomes

 

Request a kit

Preimplantation genetic testing (PGT) increases the likelihood of IVF success by helping select the best embryos.


Invitae offers two types of PGT:

PGT for chromosomal aneuploidy (PGT-A, also known as PGS)

  • This test identifies embryos with the correct number of chromosomes to improve the chances of a successful pregnancy.

  • When an embryo has extra or missing chromosomes, that’s a condition known as aneuploidy. Most aneuploid embryos do not result in a healthy live birth: many lead to spontaneous miscarriage, some fail to implant in the uterus, and some result in a baby with birth defects, intellectual disability, and/or other health problems. Aneuploidy occurs across all age groups, but after a woman reaches age 35, the proportion of aneuploid embryos increases rapidly.

PGT for structural chromosome rearrangements/translocations (PGT-SR)

  • This test evaluates embryos for unbalanced structural chromosome rearrangements (translocations). It is useful when a chromosomal translocation has previously been identified in the family.

  • Invitae’s PGT-SR also screens for chromosomal aneuploidy.

  • PGT-SR cases are accepted on a case-by-case basis. A referral form and documentation of the known translocation (karyotype) must be submitted, reviewed, and approved by the Invitae Clinical Team to determine eligibility prior to testing.

What sets Invitae’s PGT apart?

  • Accurate, timely, and actionable results

  • PGT technology that detects key chromosome abnormalities that other NGS technologies miss, including whole chromosome aneuploidy, segmental aneuploidy, triploidy, haploidy, and select uniparental isodisomy

  • Extensive validation of sensitivity and specificity

  • Patent protected, industry-leading innovation

  • CLIA-certified and CAP-accredited to perform high-complexity clinical genetic testing

How to order Invitae PGT

1. Request a collection kit at www.invitae.com/request-a-kit

2. Ship frozen trophectoderm/blastocyst biopsy samples for overnight delivery on dry ice, following the instructions included in the collection kit. The following is required for testing:

  • Test requisition form (TRF): Either a print or electronic TRF must be completed in order to proceed with testing. Download the paper TRF or talk to your Client Relationship Manager to set up an online account to order electronically.
  • Biopsy worksheet: A completed biopsy worksheet Form must accompany all samples.
  • Informed consent form: A signed PGT consent form is required in order to proceed with testing.

3. Receive results in 5-7 days of sample receipt.

  • Questions? Our team is happy to answer questions about our offering or to offer technical support. Contact us >

Take the first step by requesting a free specimen collection kit today.

Request a kit