Genetic testing for hereditary heart disease Genetic testing for hereditary heart disease

Testing for hereditary heart disease

Know your risks—and your treatment options

Genetic testing for hereditary heart disease

The genetics of hereditary heart disease

In some cases, heart disease occurs when a person inherits certain genetic variants that are associated with a disease. Hereditary heart disease may affect multiple people in one family.

When to consider genetic testing

Genetic testing may be appropriate if you (or a family member) has a known or suspected diagnosis of one or more of the following:2–7

  • a heart condition present from birth
  • cardiomyopathy
  • conditions that affect the aorta
  • genetic forms of high cholesterol and high blood pressure
  • pulmonary hypertension
  • sudden and unexplained cardiac arrest
  • unexplained irregular heartbeat (arrhythmia)

What are the benefits of testing?

Genetic testing gives you information that may help you and your healthcare provider:

  • establish or confirm your specific diagnosis
  • provide an explanation of the underlying cause of your heart condition 
  • make informed medical decisions and provide an opportunity to start risk reduction strategies
  • understand whether you are at risk of developing an underlying condition that affects more than one organ or system in your body (multisystem conditions)
  • identify other at-risk relatives for whom genetic testing is recommended 

Get a diagnostic test in two easy ways

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Get a diagnostic test online 

We can help you find a genetics provider in your area or connect you to a telemedicine provider.

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Order through your healthcare provider

Talk to your healthcare provider about diagnostic genetic testing with Invitae. This letter can help start the conversation.

Simple billing, no surprises


We’ll work directly with your insurance company so you don’t have to. Typically people pay between $0 and $100 out of pocket. Learn more.


Don’t have insurance? We offer $250 pricing and accept HSA/FSA payments. Learn more.

Genetic testing for hereditary heart disease

Testing for at-risk family members

Identifying at-risk family members is one of the most important benefits of genetic testing. If you have a genetic variant, your immediate family members have up to a 50% chance of having the same variant. Other relatives may also be at risk.

Invitae is dedicated to ensuring that both you and your family understand your risk. If you receive a positive test result from Invitae, we can test your blood relatives for that same genetic variant (change) under our family follow-up testing program.  

Genetic testing for hereditary heart disease

More than a test:
Built-in support network

You don’t have to figure it out alone. Genetics experts are available to guide you through the testing process, help you make sense of your results, and plan a path forward. 

Genetic testing for hereditary heart disease

Your questions, answered

Our resource center offers:

  • details on how the testing process works

  • downloadable guides that explain specific genetic diseases

  • an explanation of possible results and what they could mean for you

Mozaffarian, D, et al. Heart disease and stroke statistics—2015 update: a report from the American Heart Association. Circulation. 2015; 131:e29-322.
Priori, SG, et al. Heart Rhythm. 2013; 10:e85-108.
Ackerman, MJ, et al. Heart Rhythm. 201; 8:1308-39.
Goldberg AC, et al. J Clin Lipidol. 2011; 3:133-40.
Hiratzka, LF, et al. Circulation. 2010; 121:e266-369.
McLaughlin, VV, et al. J Am Coll Cardiol. 2009; 53:1573-619.
Richards AA, Garg V. Current Cardiology Reviews. 2010; 6:91-97.