Detect Hereditary Prostate Cancer

Sponsored, no-charge genetic testing and counseling for hereditary prostate cancer

Importance of germline genetic testing for prostate cancer patients

Targeted medical treatments

Genetic testing of prostate cancer enables targeted medical and surgical treatment options

Detection of other cancers

Testing can direct surveillance for, and early detection of, other DNA repair-related cancers

Family members at risk

Relatives of a patient may be at risk themselves for cancer. They may benefit from testing and early detection

1 in 6 men with prostate cancer have a germline pathogenic variant

Patient profile: BRCA2 positive

A 60-year-old male with castration-resistant prostate cancer with metastases to bone is found to have a genetic variant in BRCA2, increasing his risk of other cancers.

Increasing access to inherited genetic testing

While genetic testing offers tangible benefits to patients, it’s often underutilized due to cost and accessibility barriers. Invitae is addressing these barriers with the Detect Hereditary Prostate Cancer Program which offers no-charge, sponsored genetic testing and genetic counseling to eligible patients.

 

Patient privacy

Invitae takes patient privacy very seriously. For more information on how Invitae protects your privacy please follow this link.

Program eligibility

This program is available to males in the US and Canada with one of the following diagnoses:

  • Stage IIa, age at diagnosis 55 years or under

  • Stage IIb or IIc at any age

  • Stage III at any age

  • Stage IV at any age

Postmortem samples are not permitted through the program at this time

  • Gleason 6, age at diagnosis 55 or under

  • Gleason 7 or greater at any age

  • Metastatic disease at any age

  • Gleason undetermined, suspected low risk (stage IIa) or above at any age

Genetic testing with Invitae

The Detect Hereditary Prostate Cancer program offers testing with the Invitae Multi-Cancer Panel, the Invitae Common Hereditary Cancers Panel, and the Invitae Prostate Cancer HRR Panel. These panels test genes associated with hereditary cancer syndromes including all known prostate cancer genes.

Invitae Multi-Cancer Panel

Invitae Prostate Cancer HRR Panel

Invitae Common Hereditary Cancers Panel

Genetic counseling

Individuals testing through the Detect Hereditary Prostate Cancer program will be eligible for no-charge, post-test genetic counseling to help them understand their test results. Invitae's genetic counseling services include:

  • Review of the patient's medical and family history
  • Review of the patient's genetic test results and the implications for the patient and their family
  • A detailed consult note and pedigree made available to the patient and clinician after the counseling session

How to order

1. Submit an order

To place your online order, click here and follow the on-screen prompts.

To place a paper-based order, download the paper order form and include it in the specimen box. 

2. Collect a specimen

If a specimen collection kit was not ordered during the online ordering workflow, order a blood, buccal, or saliva collection kit here
Please view specimen and shipping requirements for important information. If you chose to do a paper-based order, include the completed paper order form in the box with the specimen.

3. Receive results

On average, results are available 10-21 days after Invitae receives the specimen. You will receive a notification email once the test results are ready.
Log in to view the status of your online order. 

Next steps and additional services

Broaden your search with re-requisition

If you don’t find answers with your initial order, Detect Hereditary Prostate Cancer includes one re-requisition within 90 days to genes within the original clinical area.

Simply log into your account, navigate to the order, and click "Add rerequisition”

Family variant testing for familial insights

If a positive result is identified, testing for your patient’s family members is available.

Simply follow the ordering instructions, selecting only the gene(s) you are interested in testing for the family member. The partner code will automatically be added with the order.

Are you a patient?

If you're a patient and believe you are eligible for this sponsored testing program, you have options:

Contact Genome Medical
(available in US only)

Schedule a genetic counseling session, by phone or video, with an expert who can review your testing options and place the order. There is a cost associated with the Genome Medical services, which may be covered under your health benefits.

Discuss the program with your doctor

If you already have a healthcare provider who can place this order, you can download this flyer to take to your own provider.

Find a local genetics provider

Search our genetics providers network to find a provider in your area. Please sign in, or create an account, to connect with our network of professionals. There may be a cost associated with the provider’s services.

Disclaimer

While third parties and commercial organizations may provide financial support for this program, tests and services are performed by Invitae. Healthcare professionals must confirm that patients meet certain criteria to use the program. Third parties and commercial organizations may receive de-identified patient data from this program, but at no time would they receive patient identifiable information. Third parties and commercial organizations may receive contact information for healthcare professionals who use this program. Genetic testing and counseling are available in the US and Canada. Healthcare professionals and patients who participate in this program have no obligation to recommend, purchase, order, prescribe, promote, administer, use or support any other products or services from Invitae or from third parties or commercial organizations.

Reference: 
1. Nicolosi P, Ledet E, Yang S et al. JAMA Oncol. 2019 Apr 1;5(4):523-528.