The Behind the Seizure® program offers Invitae's Comprehensive Epilepsy Panel to any child under the age of 8 who has had an unprovoked seizure.
An epilepsy gene panel can bring you closer to understanding what’s causing your patient’s epilepsy, helping your patients and their caregivers benefit from deeper knowledge and timely care.
More than 50% of epilepsies have some genetic basis. When a patient presents with seizures, genetic testing can help identify 100+ underlying genetic causes. Early genetic testing may be the most direct, cost-effective, and accurate diagnostic tool.1
Many genes are actionable. Gene panels increasingly help tailor your approach—more than 20 genes have been linked to specific treatment strategies. Identifying a seizure’s underlying etiology can enable more precise treatment.
Delay can be devastating for patients with genetic epilepsy. Some genetic epilepsies are neurodegenerative, and may initially present with subtle, non-specific symptoms like language development delay and/ or motor disturbance. Genetic testing can help identify the cause of epilepsy before a patient experiences the hallmark signs of regression.
Genetic epilepsies may be hiding behind non-specific symptoms. According to a poster discussing the results of an industry-sponsored test, language delay, motor disturbance, and intellectual impairment are often comoribidities and useful indicators for molecular genetic testing.2
The Behind the Seizure program accepts orders from the US and Canada.
To place a paper-based order:
Download the US order form
Download the Canadian order form
To place an order online:
To receive results:
Pal DK, et al. Genetic evaluation and counseling for epilepsy. Nat Rev Neurol. 2010;6:445-453.
Nickels KC, et al. Cognitive and neurodevelopmental comorbidities in paediatric epilepsy. Nat Rev Neurol. 2016 Aug;12(8):465-76.
Truty R et al. Possible precision medicine implications from genetic testing using combined detection of sequence and intragenic copy number variants in a large cohort with childhood epilepsy. Epilepsia Open. 2019;10:28.