Adult Neurodegenerative Disorders

Sponsored, no-charge genetic testing and counseling for individuals suspected of or at risk of having a neurodegenerative disorder either from clinical symptoms or family history.

  • UNITED STATES

  • CANADA

  • AUSTRALIA

  • BRAZIL

ALS
The annual incidence of amyotrophic lateral sclerosis (ALS) is estimated to be 4-8 per 100,000 individuals. An estimated 10% of all cases are hereditary.1,2
Parkinson Disease
Parkinson disease (PD), which is the second most common neurodegenerative condition, has an overall prevalence of 0.3% in the general population, 1-2% in individuals over age 60, and 3-4% in individuals over the age of 80. An estimated 5-10% of individuals with PD have a hereditary form.3
FTD
The annual incidence of frontotemporal dementia (FTD) has been estimated at 3.5 cases per 100,000 individuals aged 45-64 years, and is the most common type of dementia in individuals who are less than 60 years of age. It is estimated that approximately 20% of all people with FTD have a hereditary form of the condition.4,5,6

Invitae Adult Neurodegenerative Disorders sponsored testing can help:

  • Confirm a suspected diagnosis
  • Provide treatment guidance
  • Support enrollment in precision therapy clinical trials 
  • Determine which relatives may be at risk
     

About the Adult Neurodegenerative Disorders genetic testing program

Program eligibility

Symptomatic individual 18 years or older with clinical diagnosis or suspicion of one of the following conditions:
  • Amyotrophic lateral sclerosis (ALS)
  • Parkinson disease (PD)
  • Frontotemporal dementia (FTD)
  • Alzheimer disease with onset <65 years of age 
  • Hereditary prion disease 
Asymptomatic individual with: 
  • Family history of early (<65 years of age) onset diagnosis of one of the conditions above
  • A family member with a known disease-causing variant in one of the genes included on the panels offered for this program

Postmortem samples are not permitted through this program at this time

Invitae Hereditary Amyotrophic Lateral Sclerosis, Frontotemporal Dementia and Alzheimer Disease Panel* 

This panel includes genes associated with amyotrophic lateral sclerosis (ALS) and/or hereditary dementia.

*Of note, this panel does not include analysis of the C9orf72 gene at this time. 

Invitae Hereditary Parkinson Disease & Parkinsonism Panel**

This panel includes genes associated with Parkinson disease and related conditions involving parkinsonian features.

**Of note, this panel does not include analysis of all GBA gene variants at this time. Please view the panel page for details. 

How to order

1. Submit an order

To place your online order, click here and follow the on-screen prompts.

To place a paper-based order, download the paper order form and include it in the specimen box. 

2. Collect a specimen

Australian, Canadian, and US clinicians can order a blood, buccal, or saliva collection kit here. Clinicians in other eligible countries should refer to the country-specific section below for instructions on how to order a specimen collection kit in their region.
Please view specimen and shipping requirements for important information. If you chose to do a paper-based order, include the completed paper order form in the box with the specimen.

3. Receive results

On average, results are available 10-21 days after Invitae receives the specimen. You will receive a notification email once the test results are ready.
Log in to view the status of your online order. 

Country-specific program materials:

United States, Canada, and Australia:
Test Requisition Form (English)
Informed Patient Consent (English - US only)
Informed Patient Consent (English -  Outside US)
Program Flyer (English)

Brasil:
Formulário de Solicitação em papel (Português)
Formulário de Consentimento Informado do Paciente (Português)
Folheto/Panfleto do Programa e Instruções para Pedidos no Brasil (Português)

Next steps and additional services

Broaden your search with re-requisition

If you don’t find answers with your initial order, 
Adult Neurodegenerative Disorders includes one re-requisition within 90 days to genes within the original clinical area.

Simply log into your account, navigate to the order, and click "Add rerequisition”

Family variant testing for familial insights

If a positive result is identified, testing for your patient’s family members is available.

Simply follow the ordering instructions, selecting only the gene(s) you are interested in testing for the family member. The partner code will automatically be added with the order.

Are you a patient?

If you're a patient and believe you are eligible for this sponsored testing program, you have options:

Contact Genome Medical
(available in US only)

Schedule a genetic counseling session, by phone or video, with an expert who can review your testing options and place the order. There is a cost associated with the Genome Medical services, which may be covered under your health benefits.

Discuss the program with your doctor

If you already have a healthcare provider who can place this order, you can download this flyer to take to your own provider.

Find a local genetics provider

Search our genetics providers network to find a provider in your area. Please sign in, or create an account, to connect with our network of professionals. There may be a cost associated with the provider’s services.

Genetic Counseling Services (US and Canada)

Patients can schedule an appointment with Genetic Counseling Services after receiving their results:

Through the Patient Portal (preferred) - Log in to the Patient Portal and start the process under "Talk to a genetic counselor about your results." Please note this feature is only available for patients in the US and Canada.
By phone - Call Invitae Client Services at 1-800-436-3037 and ask about scheduling a genetic counseling appointment.
Online - Schedule an appointment at invitae.as.me/schedule and follow the on-screen prompts. 

Support every step of the way

Client Services

Available to answer your questions or help you through the testing process.

Clinical Support Services

Licensed, board-certified genetic counselors, ready to support you.

Prevail Therapeutics sponsors Adult Neurodegenerative Disorders genetic testing program

Prevail is a proud sponsor of Invitae’s Adult Neurodegenerative Disorders genetic testing program, helping increase access to genetic testing for individuals living with neurodegenerative disorders in the US. To learn more about Prevail, visit www.prevailtherapeutics.com.

About Invitae

Invitae Corporation (NYSE: NVTA) is a leading medical genetics company, whose mission is to bring comprehensive genetic information into mainstream medicine to improve healthcare for billions of people. Invitae's goal is to aggregate the world's genetic tests into a single service with higher quality, faster turnaround time, and lower prices. For more information, visit the company's website.